Wouldn't rule out Manfredi playing again this season, makes a nice incentive for him and with our injuries on the wing, there's a fair chance that we'll need him.
All that said, there isn't a cat in hell's chance that'd let him play any part in the Saints game, even if it means playing someone else out of position.
We'll have several games after that which are almost dead rubbers. If he's genuinely ready, play him in those.